HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophosgene → 5-(5,6-difluoro-1H-indol-2-yl)-2-methoxy-phenyl isothiocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophosgene | HCID 10040 | — |
| Reactant | 5-(5,6-difluoro1H-indol-2-yl)-2-methoxy-phenylamine | HCID 9943439 | — |
| Product | 5-(5,6-difluoro-1H-indol-2-yl)-2-methoxy-phenyl isothiocyanate | HCID 22568438 | — |
Reaction Steps
The product from Example 3, 5-(5,6-difluoro-1H-indol-2-yl)-2-methoxy-phenylamine (5.48 g, 20 mmol) was reacted with thiophosgene (1.9 mL, 25 mmol) according to the procedure for Example 26, Step A to give the product as a greenish tan solid (5.40 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06858739B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-dc5cf2e30cef4cf492296d8aa530e53a |
| Source note | uspto-grants-2005_02 |