Methanol → HCID 13878920, compound

HRID 255459Notes

Reaction equation

HRID 255459 reaction equation
C([NH:11][CH:12]([CH3:24])[CH2:13][O:14][CH:15]1[CH:19]([CH3:20])[CH2:18][CH:17](C)[C:16]1([CH3:23])[CH3:22])(OCC1C=CC=CC=1)=O.[CH3:25]O>[Pd]>[NH2:11][CH:12]([CH3:24])[CH2:13][O:14][CH:15]1[C:16]([CH3:22])([CH3:23])[CH2:17][CH2:18][C:19]1([CH3:20])[CH3:25]

Participants

4

Reactant 2

HCID 887MethanolHCID 20165746N-Cbz-1-(2-Aminopropoxy)-2,2,3,5-tetramethylcyclopentane

Product 1

HCID 13878920HCID 13878920, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

N-Cbz-1-(2-Aminopropoxy)-2,2,3,5-tetramethylcyclopentane is dissolved in CH3OH and hydrogenated over 5% Pd/C in a Parr hydrogenation apparatus. When the reaction is complete the mixture is filtered through Celite and concnetrated to yield 1-(2-amino-propoxy)-2,2,5,5-tetramethylcyclopentane.

Workup

  1. filtrationis filtered through Celite

Sources & evidence

ORD record
ord-20a12dcd95b84e54bbe4e091c67ba589
Source dataset
uspto-grants-1987_10
Patent number
US04698231

Reaction notes

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