1,4-Dibromobutane → HCID 178486057, compound

HRID 25552Notes

Reaction equation

HRID 25552 reaction equation
[C:1]([O:5][C:6](=[O:16])[N:7]([C@H:9]1[CH2:14][CH2:13][C@H:12]([OH:15])[CH2:11][CH2:10]1)[CH3:8])([CH3:4])([CH3:3])[CH3:2].[Br:17][CH2:18][CH2:19][CH2:20][CH2:21]Br>>[C:1]([O:5][C:6](=[O:16])[N:7]([C@H:9]1[CH2:10][CH2:11][C@H:12]([O:15][CH2:21][CH2:20][CH2:19][CH2:18][Br:17])[CH2:13][CH2:14]1)[CH3:8])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 178486055HCID 178486055, compound

Product 1

HCID 178486057HCID 178486057, compound

Procedure

In analogy to example 11.5, trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester and 1,4-dibrombutane were reacted to yield trans-[4-(4-Bromo-butoxy)-cyclohexyl]-methyl-carbamic acid tert-butyl ester as yellowish oil, MS: 364 (MH+, 1Br).

Sources & evidence

ORD record
ord-652cc05d065f4b3785e7c8fccfe172f1
Source dataset
uspto-grants-2005_02
Patent number
US06858651B2

Reaction notes

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