Triethyl orthoacetate → HCID 178432311, compound

HRID 255540Notes

Reaction equation

HRID 255540 reaction equation
[NH2:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1[NH2:12])=[CH:9][CH:8]=[CH:7][CH:6]=2.[C:13](OCC)(OCC)(OCC)[CH3:14]>>[CH3:13][C:14]1[NH:12][C:11]2[C:10]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=3[N:4]=[CH:3][C:2]=2[N:1]=1

Participants

3

Reactant 2

HCID 66221Triethyl orthoacetateHCID 15142893,4-Diaminoquinoline

Product 1

HCID 178432311HCID 178432311, compound

Procedure

Using the method of Example 147, 3,4-diaminoquinoline (from Example 39) was reacted with triethyl orthoacetate to provide 2-methyl-1H-imidazo[4,5-c]quinoline as a tan solid, m.p. 242°-245° C.

Sources & evidence

ORD record
ord-3fef86f536de4fd38526d113f9a63518
Source dataset
uspto-grants-1987_10
Patent number
US04698348

Reaction notes

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