Sodium Methoxide → HCID 13958462, compound

HRID 255545Notes

Reaction equation

Cl[C:2]1[C:11]2[N:12]=[CH:13][N:14]([CH3:15])[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1.[CH3:16][O-:17].[Na+]>>[CH3:16][O:17][C:2]1[C:11]2[N:12]=[CH:13][N:14]([CH3:15])[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1

Participants

Reactant 2

HCID 10942334Sodium Methoxide

HCID 13958418HCID 13958418, compound

Product 1

HCID 13958462HCID 13958462, compound

Procedure

Using the method of Example 157, 4-chloro-1-methyl-1H-imidazo[4,5-c]quinoline (from Example 114) was reacted with sodium methoxide to provide 4-methoxy-1-methyl-1H-imidazo[4,5-c]quinoline, melting point after recrystallization from ethyl acetate 160°-162° C. Analysis: Calculated for C12H11N3O: %C, 67.6; %H, 5.2; N, 19.7; Found: %C, 67.3; %H, 5.0; %N, 19.8.

Sources & evidence

ORD record: ord-ce36bd3bc21e4d23b25ff20ad36db9b9
Source dataset: uspto-grants-1987_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04698348

Reaction notes

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