HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl orthoacetate → 1-benzyl-2-methyl-1H-imidazo[4,5-c]quinoline hydrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl orthoacetate | HCID 66221 | — |
| Reactant | HCID 15224414 | HCID 15224414 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 1-benzyl-2-methyl-1H-imidazo[4,5-c]quinoline hydrate | HCID 13958470 | — |
Reaction Steps
Using the method of Example 49, 3-amino-4-(benzylamino)quinoline (from Example 127, Part B), was reacted with triethyl orthoacetate and acetic acid to provide 1-benzyl-2-methyl-1H-imidazo[4,5-c]quinoline hydrate, m.p. 145°-147° C. Analysis: Calculated for C18H15N3.2.25H2O: %C, 68.9; %H, 6.3, %N, 13.4; Found: %C, 69.2; %H, 6.0; %N 13.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04698348 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-3daa445cd6284cb1bde5659cc5c50559 |
| Source note | uspto-grants-1987_10 |