2-Propanol, 1-amino-2-methyl- → 2-Methyl-1-((3-nitroquinolin-4-yl)amino)propan-2-ol

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Reaction Steps

Using the method of Example 1, 4-chloro-3-nitroquinoline was reacted with 2-hydroxy-2-methylpropylamine to provide 4-(2-hydroxy-2-methylpropylamino)-3-nitroquinoline, m.p. 234°-244° C.(dec.). Analysis: Calculated for C13H15N3O3 : %C, 59.8; %H, 5.8; %N, 16.0; Found: %C, 59.8; %H, 5.9; %N, 16.1.

Provenance & Evidence