Benzyloxycarbonylglycine → HCID 178512894, compound

HRID 255628Notes

Reaction equation

C([NH:11][C@H:12]([C:20]([NH:22][CH2:23][C:24]([NH:26][C@H:27]([C:35]([OH:37])=[O:36])[CH2:28][CH2:29][CH2:30][NH:31][C:32](=[NH:34])[NH2:33])=[O:25])=[O:21])[CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(OCC1C=CC=CC=1)=O.[C:38]([NH:48][CH2:49][C:50]([OH:52])=O)([O:40][CH2:41][C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1)=[O:39]>>[C:38]([NH:48][CH2:49][C:50]([NH:11][C@H:12]([C:20]([NH:22][CH2:23][C:24]([NH:26][C@H:27]([C:35]([OH:37])=[O:36])[CH2:28][CH2:29][CH2:30][NH:31][C:32](=[NH:33])[NH2:34])=[O:25])=[O:21])[CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:52])([O:40][CH2:41][C:42]1[CH:43]=[CH:44][CH:45]=[CH:46][CH:47]=1)=[O:39]

Participants

Reactant 2

HCID 14349Benzyloxycarbonylglycine

HCID 178512895HCID 178512895, compound

Product 1

HCID 178512894HCID 178512894, compound

Procedure

Carbobenzoxy-glycyl-phenylalanyl-glycyl-arginine is prepared by the method similar to that described for the preparation of carbobenzoxy-phenylalanyl-glycyl-arginine on the basis of 2.71 g (5.28 mM) of the latter and 1.93 g (5.83 mM) of p-nitrophenyl ester of carbobenzoxy-glycin.

Sources & evidence

ORD record: ord-146d343ee2b543f799ecf923b0d373eb
Source dataset: uspto-grants-1987_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04698419

Reaction notes

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