HCID 20184039, compound → HCID 20184137, compound

HRID 255695Notes

Reaction equation

HRID 255695 reaction equation
[N+:1]([C:4]1[C:5]([N:10]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:11][CH2:12][CH2:13][N:14]2[C:22](=[O:23])[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[C:15]2=[O:24])=[N:6][CH:7]=[CH:8][CH:9]=1)([O-])=O.[H][H]>[Pd].C(O)C.C(OCC)(=O)C>[NH2:1][C:4]1[C:5]([N:10]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:11][CH2:12][CH2:13][N:14]2[C:15](=[O:24])[C:16]3[C:21](=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:22]2=[O:23])=[N:6][CH:7]=[CH:8][CH:9]=1

Participants

5

Reactant 2

HCID 20184039HCID 20184039, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 20184137HCID 20184137, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 21584252Ethanol ethylacetateSolvent

Procedure

2-[3-[(3-Nitro-2-pyridinyl)phenylamino]propyl]-1H-isoindole-1,3(2H)dione is reduced with hydrogen and palladium-on-carbon catalyst in ethanol-ethyl acetate mixtures to give the title compound.

Sources & evidence

ORD record
ord-a6eac7fe4bcf4f888cb14bedda0c952b
Source dataset
uspto-grants-1987_10
Patent number
US04698430

Reaction notes

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