Hydrochloric Acid → HCID 178511443, compound

Participants

Reaction Steps

7-[2-(2-formamidothiazol-4-yl)-2-(2-tert-butoxycarbonylaminoethoxyimino)acetamido]-3-(1H-1,2,3-triazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid (syn isomer, 2.1 g.) was treated with conc. hydrochloric acid (1.3 g.) in a similar manner to that of Example 21-(2) to give 7-[2-(2-aminothiazol-4-yl)-2-(aminoethoxyimino)acetamido]-3-(1H-1,2,3-triazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid (syn isomer, 0.7 g.).

Provenance & Evidence