HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Hydroximinomethyl)cinnoline → 4-Cinnolinecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Hydroximinomethyl)cinnoline | HCID 136393710 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 4-Cinnolinecarbonitrile | HCID 593257 | — |
Reaction Steps
A stirred solution of 0.173 g of 27B in 5 ml of acetic anhydride was refluxed overnight under nitrogen. The mixture was stripped under reduced pressure, and the residue was recrystallized from hexane to give cinnoline-4-carbonitrile (27C), as a yellow crystalline solid, m.p.: 140° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04699651 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-980cdb1f545344bbadc9e514bab5e0be |
| Source note | uspto-grants-1987_10 |