2-(2-Amino-3-methylphenyl)propan-2-ol → 2-Methyl-6-(prop-1-en-2-yl)aniline

HRID 255858노트

반응식

HRID 255858 반응식
[NH2:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]([CH3:12])([CH3:11])O>C1(C)C=CC=CC=1.II>[NH2:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]([CH3:12])=[CH2:11]

참가 물질

4

반응물 1

HCID 139590002-(2-Amino-3-methylphenyl)propan-2-ol

생성물 1

HCID 139590022-Methyl-6-(prop-1-en-2-yl)aniline

시약·촉매·용매 2

HCID 807Iodine용매HCID 1140Toluene용매

실험 절차

49B was dissolved in 60 ml of toluene containing 5 mg of iodine, and the mixture was refluxed overnight. The solvent was evaporated and the residue was distilled in a short-path bantumware apparatus to give 2-(2-amino-3-methylphenyl)propene (49C), as a colorless oil, b.p.: 82°-85° C. (2 Torr.).

후처리

  1. temperaturethe mixture was refluxed overnight
  2. customThe solvent was evaporated
  3. distillationthe residue was distilled in a short-path bantumware apparatus

출처 및 근거

ORD 기록
ord-80b87f98e2ff41768a4be73f5b0294b0
출처 데이터셋
uspto-grants-1987_10
특허 번호
US04699651

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