Sulfuric Acid → HCID 13959016, compound

Participants

Reaction Steps

1.4 g of 53G was dissolved in 60 ml of 50% aqueous sulfuric acid and the mixture was stirred at 90°-100° C. for 32 hours. The mixture was cooled and made basic with 50% aqueous potassium hydroxide solution, then filtered. The filtrate was extracted with ether. The aqueous phase was acidified with 12 N hydrochloric acid and filtered. The resulting solid was dissolved in ethyl acetate, the solution was dried and stripped of solvent to give 53, as a solid, m.p.: 175°-176° C. (with decomposition).

Provenance & Evidence