Tetrahydrofuran → HCID 13959038, compound

Participants

Reaction Steps

A solution of 1.1 g of 53, 70 ml of dry THF and 0.98 g of CDII was stirred under nitrogen at room temperature until no more gas evolved (4 hours), 0.35 g of methanol and 0.03 g of sodium acetate were added and the mixture was stirred at room temperature for 3 hours. The THF was evaporated, the residue was dissolved in methylene chloride, the solution was washed with water, dried (MgSO4) and stripped of solvent. The residue was recrystallized from hexane to give 54, as a yellow solid, m.p.: 59°-60° C.

Provenance & Evidence