HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → Methyl 2-(o-Methoxyphenylthio)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 2-[(2-Methoxyphenyl)sulfanyl]benzoic acid | HCID 15573887 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 2-(o-Methoxyphenylthio)benzoate | HCID 13338684 | — |
Reaction Steps
Dissolve 115 g of the acid of Step A in 3.5 liters of methanol and add slowly 25 ml of sulfuric acid. Stir under reflux for 72 hours. Cool the reaction mixture to room temperature and add 100 g of sodium bicarbonate in portions. Stir for an additional hour and strip to dryness. Dissolve the residue in methylene chloride and wash the solution three times with water. Dry the solution and strip to an oil which solidifies. (m.p. 82°-84° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04699917 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-c9a268cd04b44c9c82fdaea328c1ec99 |
| Source note | uspto-grants-1987_10 |