HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-(o-Carboxyphenylthio)-4-hydroxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Formate | HCID 2723810 | — |
| Reactant | 3-(o-Carboxyphenylthio)-4-hydroxybenzaldehyde | HCID 13338686 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 3-(o-Carboxyphenylthio)-4-hydroxybenzonitrile | HCID 13338687 | — |
Reaction Steps
Reflux 91.3 g of the aldehyde of Step D, 27.4 g of hydroxylamine hydrochloride and 41.9 g of sodium formate in 900 ml of formic acid (98-100%) for 11/4 hours. Cool the mixture and pour into 21/2 liters of cold water. Separate the precipitate, wash with water and dry in vacuo at 75° C. (Yield: 82 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04699917 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-e991433f690d41b7af81455b646585f9 |
| Source note | uspto-grants-1987_10 |