Trifluoroacetic acid → alpha-{6-[1-Ethoxycarbonyl-3-phenylpropylamino]-5-oxo-2-phenylperhydro-1,4-thiazepin-4-yl}acetic acid

Participants

Reaction Steps

0.28 g of t-butyl α-{6-[1-ethoxycarbonyl-3-phenylpropylamino]-5-oxo-2-phenylperhydro-1,4-thiazepin-4-yl}acetate [prepared as described in Example 7(i) above (the first fraction)] was subjected to de-t-butylation with trifluoracetic acid in the same manner as described in Example 3, giving the title compound as an amorphous solid in a yield of 0.18 g.

Provenance & Evidence