HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → alpha-{6-[1-Carboxy-3-phenylpropylamino]-5-oxo-2-phenylperhydro-1,4-thiazepin-4-yl}acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | alpha-{6-[1-Ethoxycarbonyl-3-phenylpropylamino]-5-oxo-2-phenylperhydro-1,4-thiazepin-4-yl}acetic acid | HCID 13877897 | — |
| Product | alpha-{6-[1-Carboxy-3-phenylpropylamino]-5-oxo-2-phenylperhydro-1,4-thiazepin-4-yl}acetic acid | HCID 13877902 | — |
Reaction Steps
50 mg of α-{6-[1-ethoxycarbonyl-3-phenylpropylamino]-5-oxo-2-phenylperhydro-1,4-thiazepin-4-yl}acetic acid (prepared as described in Example 11 above) was hydrolyzed with aqueous sodium hydroxide in the manner described in Example 5, giving the title compound as a powder in a yield of 40 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04699905 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-3e83702897cb425eb22b57cb8e8e0d21 |
| Source note | uspto-grants-1987_10 |