HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl bromoacetate → t-butyl alpha-[5-oxo-6(R)-phthalimido-3(S)-(2-thienyl)perhydro-1,4-thiazepin-4-yl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | 5-oxo-6(R)-phthalimido-3(S)-(2-thienyl)perhydro-1,4-thiazepine | HCID 13877946 | — |
| Product | t-butyl alpha-[5-oxo-6(R)-phthalimido-3(S)-(2-thienyl)perhydro-1,4-thiazepin-4-yl]acetate | HCID 13877949 | — |
Reaction Steps
1.3 g of 5-oxo-6(R)-phthalimido-3(S)-(2-thienyl)perhydro-1,4-thiazepine [prepared as described in step (e) above] was treated with t-butyl bromoacetate in the manner described in Example 1(f), to give 0.99 g of the title compound as crystals, melting at 211°-212° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04699905 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-2da7fd75be324f119d3d0d483f167d8d |
| Source note | uspto-grants-1987_10 |