HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → alpha-[6-(1-Carboxy-3-phenylpropylamino)-2-(2-naphthyl)-5-oxoperhydro-1,4-thiazepin-4-yl]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 20164862 | HCID 20164862 | — |
| Product | alpha-[6-(1-Carboxy-3-phenylpropylamino)-2-(2-naphthyl)-5-oxoperhydro-1,4-thiazepin-4-yl]acetic acid | HCID 20164820 | 70.3% |
Reaction Steps
200 mg of α-[6-(1-ethoxycarbonyl-3-phenylpropylamino)-2-(2-naphthyl)-5-oxoperhydro-1,4-thiazepin-4-yl]acetic acid (prepared as described in Example 40 above) were hydrolyzed with aqueous sodium hydroxide in the same manner as described in Example 38, to give 133 mg of the title compound as a powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04699905 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-1a777d6804814597b52bd7a66fe6ed92 |
| Source note | uspto-grants-1987_10 |