Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 256074Generated: October 31, 2026

Sodium Hydroxide → alpha-[6-(1-Carboxy-3-phenylpropylamino)-2-(2-furyl)-5-oxoperhydro-1,4-thiazepin-4-yl]acetic acid

https://huagongshe.com/reaction/256074

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactantalpha-[6-(1-Ethoxycarbonyl-3-phenylpropylamino)-2-(2-furyl)-5-oxoperhydro-1,4-thiazepin-4-yl]acetic acidHCID 20164816—
Productalpha-[6-(1-Carboxy-3-phenylpropylamino)-2-(2-furyl)-5-oxoperhydro-1,4-thiazepin-4-yl]acetic acidHCID 2016492171.3%

Reaction Steps

Following the procedure described in Example 44, 130 mg of α-[6-(1-ethoxycarbonyl-3-phenylpropylamino)-2-(2-furyl)-5-oxoperhydro-1,4-thiazepin-4-yl]acetic acid (prepared as described in Example 57 above) were hydrolyzed with sodium hydroxide, to afford 87 mg of the title compound as a powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04699905
Source datasetuspto-grants-1987_10
ORD IDord-89a6793f1a7546d9a5a72a6477e45444
Source noteuspto-grants-1987_10