HCID 13877864, compound → HCID 13877870, compound

HRID 256086Notes

Reaction equation

HRID 256086 reaction equation
[C:1]([O:5][C:6]([NH:8][C@H:9]([C:22]([OH:24])=[O:23])[CH2:10][S:11][CH:12]([C:17]1[CH:21]=[CH:20][S:19][CH:18]=1)[CH2:13][N+:14]([O-])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[H][H]>[Pd]>[NH2:14][CH2:13][CH:12]([S:11][CH2:10][C@@H:9]([C:22]([OH:24])=[O:23])[NH:8][C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:7])[C:17]1[CH:21]=[CH:20][S:19][CH:18]=1

Participants

4

Reactant 2

HCID 13877864HCID 13877864, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 13877870HCID 13877870, compoundYield 73.2%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

74.8 g of N-t-butoxycarbonyl-S-[2-nitro-1-(3-thienyl)ethyl]-L-cysteine were reduced with hydrogen in the presence of 10% w/w palladium-on-carbon, as described in Example 63(b), to give 50.4 g of the title compound as a powder.

Sources & evidence

ORD record
ord-9d04430431814822913f27872221446e
Source dataset
uspto-grants-1987_10
Patent number
US04699905

Reaction notes

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