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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25616Generated: October 25, 2026

Methylamine → HCID 178483439, compound

https://huagongshe.com/reaction/25616

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantTrifluoroacetic acidHCID 6422—
Reactant4-(Trifluoromethyl)phenyl carbonochloridateHCID 15917597—
ReactantHCID 178484796HCID 178484796—
ProductHCID 178483439HCID 178483439—

Reaction Steps

In analogy to examples 29.10 and 29.11, trans-Methansulfonic acid 5-(4-methyl amino-cyclohexyl)-pentyl ester.trifluoroacetic acid salt and 4-trifluoromethyl-phenyl chloroformate were reacted, followed by treatment with methylamine to give trans-Methyl-[4-(5-methylamino-pentyl)-cyclohexyl]-carbamic acid 4-trifluoromethyl-phenyl ester, MS: 401 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06858651B2
Source datasetuspto-grants-2005_02
ORD IDord-526555117a2b4031930b54adf72a3654
Source noteuspto-grants-2005_02