HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 4-Bromomethyl-2-fluoropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 2-Fluoro-4-methylpyridine | HCID 2737403 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-Bromomethyl-2-fluoropyridine | HCID 13985168 | 24.4% |
Reaction Steps
By the method of Example 20, 10 g (0.09 mole) of 2-fluoro-4-methylpyridine and 16 g (0.09 mole) of N-bromosuccinimide were reacted in 90 ml of carbon tetrachloride to produce 4.18 g 4-bromomethyl-2-fluoropyridine. The ir, proton nmr, and 19F nmr spectra were all consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04701464 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-34c5140a392d4dbeb1659ba46ee7b0da |
| Source note | uspto-grants-1987_10 |