HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl 5-hydantoylphosphonate → N-Cyclohexyl-1-[3-[(2,4-dioxoimidazolidin-5-ylidene)methyl]-4-nitrophenyl]-N-methyl-3-piperidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl 5-hydantoylphosphonate | HCID 3516088 | — |
| Reactant | 2-nitro-5-[3-(N-methyl-N-cyclohexylcarbamoyl)-1-piperidinyl]benzaldehyde | HCID 20164152 | — |
| Product | N-Cyclohexyl-1-[3-[(2,4-dioxoimidazolidin-5-ylidene)methyl]-4-nitrophenyl]-N-methyl-3-piperidinecarboxamide | HCID 53710199 | — |
Reaction Steps
Prepared from diethyl 2,4-dioxoimidazolidine-5-phosphonate and 2-nitro-5-[3-(N-methyl-N-cyclohexylcarbamoyl)-1-piperidinyl]benzaldehyde analogous to the procedure of Example (2-1), m.p. 153°-162° C., crystallized from MeOH-H2O.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04701459 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-57ba92b17d924b00b54ea524b9726496 |
| Source note | uspto-grants-1987_10 |