Diisobutylaluminumhydride → HCID 57311870, compound

Participants

Reaction Steps

15.5 ml of a toluene solution of 20% of diisobutyl aluminum hydride were slowly added at -70° C. to a solution of 2.5 g of the product of Step B in 25 ml of toluene with stirring and the mixture was poured over ice. The mixture was filtered and the filtrate was extracted with ether and was evaporated to dryness under reduced pressure to obtain 2.5 g of (1R,2R,4R,5S) 6,6-dimethyl-4-(2-methyl-prop-2-yl)-3-oxa-bicyclo(3,1,0)hexan-2-ol melting at 126° C.

Provenance & Evidence