HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Amino-4-(2,2,5,5-tetramethyl-1-cyclopentyl)-3-butene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | N-Boc-2-amino-4-(2,2,5,5-tetramethyl-1-cyclopentyl)-3-butene | HCID 70445522 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 2-Amino-4-(2,2,5,5-tetramethyl-1-cyclopentyl)-3-butene | HCID 57252984 | — |
Reaction Steps
N-Boc-2-amino-4-(2,2,5,5-tetramethyl-1-cyclopentyl)-3-butene is dissolved in trifluoroacetic acid and the solution is stirred overnight. Water is added and the mixture is made basic with 20% KOH. The mixture is extracted with ether, and the organic layer is dried over Na2SO4 and evaporated to yield 2-amino-4-(2,2,5,5-tetramethyl-1-cyclopentyl)-3-butene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04701552 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-6328da06b7584f319264bc9fd52ca6b6 |
| Source note | uspto-grants-1987_10 |