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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25626Generated: October 25, 2026

Trifluoroacetic acid → HCID 178457217, compound

https://huagongshe.com/reaction/25626

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantN-MethylallylamineHCID 69391—
Reactant4-(Trifluoromethyl)benzenesulfonyl chlorideHCID 2777399—
ReactantHCID 178484800HCID 178484800—
ProductHCID 178457217HCID 178457217—

Reaction Steps

In analogy to examples 31.5 and 31.6, trans-Methanesulfonic acid 4-(4-methylamino-cyclohexyl)-butyl ester.trifluoro-acetic acid and and 4-trifluoromethyl-phenyl-sulfonylchloride were reacted, followed by treatment with N-allyl-N-methylamine to give trans-N-{4-[4-(Allyl-methyl-amino)-butyl]-cyclohexyl}-N-methyl-4-trifluoromethyl-benzenesulfonamide, MS: 447 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06858651B2
Source datasetuspto-grants-2005_02
ORD IDord-9b7c69e8bf6440608ef6f7ab93b482bf
Source noteuspto-grants-2005_02