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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25628Generated: October 25, 2026

Trifluoroacetic acid → HCID 178484798, compound

https://huagongshe.com/reaction/25628

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantPiperidineHCID 8082—
Reactant4-(Trifluoromethyl)benzenesulfonyl chlorideHCID 2777399—
ReactantHCID 178484800HCID 178484800—
ProductHCID 178484798HCID 178484798—

Reaction Steps

In analogy to examples 31.5 and 31.6, trans-Methanesulfonic acid 4-(4-methylamino-cyclohexyl)-butyl ester.trifluoro-acetic acid and 4-trifluoromethyl-phenyl-sulfonylchloride were reacted, followed by treatment with piperidine to give trans-N-Methyl-N-[4-(4-piperidin-1-yl-butyl)-cyclohexyl]-4-trifluoromethyl-benzenesulfonamide, MS: 461 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06858651B2
Source datasetuspto-grants-2005_02
ORD IDord-e74626a95eab41999b9c302c2e05234f
Source noteuspto-grants-2005_02