反应详情

To a solution of 3.46 g (0.021 mole) of 2,2-dimethyl-4-hydroxymethyl-1,3-dithiolan in 15 mL of toluene was added dropwise 2.35 g (0.020 mole) of thionyl chloride, and the mixture was heated gradually to 80°-85° C., maintained at that temperature for 0.75 hour, then stirred at room temperature for 16 hours. The mixture was filtered, and the filtrate concentrated to dryness at 60° C./100 mm Hg to give a residual oil. Distillation of the oil gave 1.81 g of product, bp 75°-78° C./1.25-1.35 mm Hg.

1. temperaturethe mixture was heated gradually to 80°-85° C.
2. temperaturemaintained at that temperature for 0.75 hour
3. filtrationThe mixture was filtered
4. concentrationthe filtrate concentrated to dryness at 60° C./100 mm Hg
5. customto give a residual oil
6. distillationDistillation of the oil