Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25630Generated: October 26, 2026

Trifluoroacetic acid → HCID 178457218, compound

https://huagongshe.com/reaction/25630

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantN-MethylpropylamineHCID 12315—
Reactant4-(Trifluoromethyl)benzenesulfonyl chlorideHCID 2777399—
ReactantHCID 178484800HCID 178484800—
ProductHCID 178457218HCID 178457218—

Reaction Steps

In analogy to examples 31.5 and 31.6, trans-Methanesulfonic acid 4-(4-methylamino-cyclohexyl)-butyl ester.trifluoro-acetic acid and 4-trifluoromethyl-phenyl-sulfonylchloride were reacted, followed by treatment with methyl-propyl-amine to give trans-N-Methyl-N-{4-[4-(methyl-propyl-amino)-butyl]-cyclohexyl}-4-trifluoromethyl-benzenesulfonamide, MS: 449 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06858651B2
Source datasetuspto-grants-2005_02
ORD IDord-87ca8e65c17446c9b2bcadba7e18d7f8
Source noteuspto-grants-2005_02