Stearic Acid → Azulenesulfonic acid

HRID 256300Notes

Reaction equation

HRID 256300 reaction equation
[C:1]1([S:11]([O-:14])(=[O:13])=[O:12])[C:10]2[C:4]([CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)=[CH:3][CH:2]=1.[Na+].C(O)(=O)CCCCCCCCCCCCCCCCC>>[C:1]1([S:11]([OH:14])(=[O:12])=[O:13])[C:10]2[C:4]([CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 5281Stearic AcidHCID 23702350HCID 23702350, compound

Product 1

HCID 9834293Azulenesulfonic acidYield 0%

Conditions

Temperature
80 °C

Procedure

Sodium azulenesulfonate (12 g), 186 g of hydroxypropylcellulose-M and 282 g of stearic acid were granulated by the same way as in Example 5. Each 160 mg of it was filled in a capsule No. 3. The capsules were placed in a fluidized bed granulator-drier, fluidized by heating with air (intake temperature: 80° C.) for 15 minutes, the heater was turned off and allowed to cool with air of the room temperature to give capsules each containing 4 mg of azulenesulfonic acid.

Workup

  1. additionEach 160 mg of it was filled in a capsule No
  2. temperatureto cool with air of the room temperature

Sources & evidence

ORD record
ord-d8bbaed987ed479a8c9abd44a4e1fad7
Source dataset
uspto-grants-1987_10
Patent number
US04702918

Reaction notes

Loading…