Acetic Anhydride → HCID 54005521, compound

Participants

Reaction Steps

103 g (0.37 mole) of the resulting ester and 83 g (0.56 mole) of triethyl orthoformate are heated at 150°-160° C. with 95 g of acetic anhydride for 2 hours and the mixture is subsequently concentrated at 120°-130° C. under normal pressure and then under a high vacuum. 115 g (92% of theory) and ethyl 2-(5-chloro-2,3,4-trifluoro-benzoyl)-3-ethoxyacrylate are obtained as an oil.

Provenance & Evidence