Acetic Anhydride → HCID 13669921, compound

HRID 256321Notes

Reaction equation

[CH2:1]([C:3]1[C:4]([O:17][CH3:18])=[N:5][C:6]2[N:7]([CH:10]=[C:11]([C:13]([NH:15][NH2:16])=[O:14])[N:12]=2)[C:8]=1[CH3:9])[CH3:2].[C:19](OC(=O)C)(=O)[CH3:20]>>[CH2:1]([C:3]1[C:4]([O:17][CH3:18])=[N:5][C:6]2[N:7]([CH:10]=[C:11]([C:13]3[O:14][C:19]([CH3:20])=[N:16][N:15]=3)[N:12]=2)[C:8]=1[CH3:9])[CH3:2]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 13669920HCID 13669920, compound

Product 1

HCID 13669921HCID 13669921, compoundYield 34%

Procedure

Using the procedure of Steps B and C of Example 3, 6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidine-2-carbohydrazide and acetic anhydride were reacted to obtain a 34% yield of 6-ethyl-7-methoxy-5-methyl-2-(5-methyl-1,3,4-oxadiazol-2-yl)imidazo[1,2-a]pyrimidine.

Workup

customwere reacted

Sources & evidence

ORD record: ord-63a4b3788e5f4886bc502f7c65d5df53
Source dataset: uspto-grants-1987_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04703049

Reaction notes

Loading…