Triethyl orthoacetate → HCID 13669935, compound

Participants

Reaction Steps

A mixture of 3.58 g of 6-allyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidine-2-carbohydrazide and 25 cm3of triethyl orthoacetate was heated at 150°-180° C. for 16 hours. The mixture was then cooled and evaporated to dryness and the resulting crude product purified by flash chromatography to obtain 1.47 g of 6-allyl-7-methoxy-5-methyl-2-(5-methyl-1,3,4-oxadiazol-2-yl)imidazo[1,2-a]pyrimidine.

Provenance & Evidence