Benzyloxycarbonylglycine → HCID 20163739, compound

HRID 256374Notes

Reaction equation

[CH3:1][C:2]1([CH3:13])[NH:6][CH:5]([CH3:7])[C:4](=[O:8])[N:3]1[CH2:9][C:10]([NH2:12])=[O:11].[CH2:14]([O:21][C:22]([NH:24][CH2:25][C:26](O)=[O:27])=[O:23])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([O:21][C:22]([NH:24][CH2:25][C:26]([N:6]1[CH:5]([CH3:7])[C:4](=[O:8])[N:3]([CH2:9][C:10]([NH2:12])=[O:11])[C:2]1([CH3:1])[CH3:13])=[O:27])=[O:23])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

Reactant 2

HCID 14349Benzyloxycarbonylglycine

HCID 20155476HCID 20155476, compound

Product 1

HCID 20163739HCID 20163739, compound

Procedure

The same procedure of Example 2, starting from 2,2,4- trimethyl-5-oxo-1-imidazolidineacetamide and N-benzyloxycarbonylglycine, afforded 3-(2-benzyloxycarbonylaminoacetyl)-2,2,4-trimethyl-5-oxo-1-imidazolidineacetamide, as an oil, then the title compound, m.p. 118° C. Mass spectrum (E.I., 70 eV, 1.5 mA), m/z=212 (M.+ --CH4N), 184 (M.+ --C2H4NO).

Sources & evidence

ORD record: ord-7695506ad19b4e008ccb76d30af2285f
Source dataset: uspto-grants-1987_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04703054

Reaction notes

Loading…