Acetic Anhydride → HCID 20163745, compound

HRID 256375Notes

Reaction equation

HRID 256375 reaction equation
[NH2:1][CH2:2][C:3]([N:5]1[CH2:9][C:8](=[O:10])[N:7]([CH2:11][C:12]([NH2:14])=[O:13])[C:6]1([CH3:16])[CH3:15])=[O:4].[C:17](OC(=O)C)(=[O:19])[CH3:18]>>[C:17]([NH:1][CH2:2][C:3]([N:5]1[CH2:9][C:8](=[O:10])[N:7]([CH2:11][C:12]([NH2:14])=[O:13])[C:6]1([CH3:16])[CH3:15])=[O:4])(=[O:19])[CH3:18]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 20163706HCID 20163706, compound

Product 1

HCID 20163745HCID 20163745, compound

Procedure

A solution of 3-(2-aminoacetyl)-2,2-dimethyl-5-oxo-1-imidazolidineacetamide (2 g) in acetic anhydride (10 ml) was stirred at 80° C. for 5 minutes. After cooling, the precipitate was collected and washed with acetone, affording the title compound as a white powder, m.p. 222° C. dec.

Workup

  1. temperatureAfter cooling
  2. customthe precipitate was collected
  3. washwashed with acetone

Sources & evidence

ORD record
ord-6d5b06e2fa8242a49b37a42c826f4764
Source dataset
uspto-grants-1987_10
Patent number
US04703054

Reaction notes

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