1-Pyrrolidineacetic acid, 4-hydroxy-2-oxo-, (+-)- → HCID 20163741, compound

HRID 256378Notes

Reaction equation

HRID 256378 reaction equation
[OH:1][CH:2]1[CH2:6][N:5]([CH2:7][C:8]([OH:10])=O)[C:4](=[O:11])[CH2:3]1.[CH3:12][C:13]1([CH3:19])[NH:17][C:16](=[O:18])[CH2:15][NH:14]1>>[CH3:12][C:13]1([CH3:19])[NH:17][C:16](=[O:18])[CH2:15][N:14]1[C:8](=[O:10])[CH2:7][N:5]1[CH2:6][CH:2]([OH:1])[CH2:3][C:4]1=[O:11]

Participants

3

Reactant 2

HCID 111265411-Pyrrolidineacetic acid, 4-hydroxy-2-oxo-, (+-)-HCID 212792952,2-Dimethylimidazolidin-4-one

Product 1

HCID 20163741HCID 20163741, compound

Procedure

The same procedure of Example 10, starting from 4-hydroxy-2-oxo-1-pyrrolidineacetic acid and 2,2-dimethyl-4-imidazolidinone, afforded the title compound, m.p. 250° C. (dec).

Sources & evidence

ORD record
ord-e298c2b6726c40029f7f3a0c9c634bce
Source dataset
uspto-grants-1987_10
Patent number
US04703054

Reaction notes

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