HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pyrrolidineacetic acid, 4-hydroxy-2-oxo-, (+-)- → 1-[2-(4-Hydroxy-2-oxo-1-pyrrolidineacetamido)acetyl]-2,2,5-trimethyl-4-imidazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pyrrolidineacetic acid, 4-hydroxy-2-oxo-, (+-)- | HCID 11126541 | — |
| Reactant | 1-(2-Aminoacetyl)-2,2,5-trimethyl-4-imidazolidinone | HCID 20163748 | — |
| Product | 1-[2-(4-Hydroxy-2-oxo-1-pyrrolidineacetamido)acetyl]-2,2,5-trimethyl-4-imidazolidinone | HCID 54224600 | — |
Reaction Steps
The same procedure of Example 11, starting from 4-hydroxy-2-oxo-1-pyrrolidineacetic acid and 1-(2-aminoacetyl)-2,2,5-trimethyl-4-imidazolidinone, gave the title compound as a diastereoisomeric mixture, m.p. 218°-220° C. Mass spectrum (E.I., 70 eV, 1.5 mA), m/z=269 (M.+ --C3H7N).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04703054 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-2118975caecb4611aaab8278e4068f83 |
| Source note | uspto-grants-1987_10 |