Hydrochloric Acid → HCID 131715351, compound

Participants

Reaction Steps

7-[2-(2-Formamido-5-methylthiazol-4-yl)-2-methoxyiminoacetamido]-3-(1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid (syn isomer, 2.4 g.) was treated with conc. hydrochloric acid (1.3 ml.) in a similar manner to that of Example 1-(2) to give 7-[2-(2-amino-5-methylthiazol-4-yl)-2-methoxyiminoacetamido]-3-(1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid hydrochloride (syn isomer, 2.3 g.).

Provenance & Evidence