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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 256452Generated: October 30, 2026

Diethyl Ether → HCID 131715367, compound

https://huagongshe.com/reaction/256452

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantDiisopropyl EtherHCID 7914—
ReactantHCID 131715366HCID 131715366—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 131715367HCID 13171536752.1%

Reaction Steps

A solution of 4-nitrobenzyl 7-[2-(2-formamido-5-bromothiazol-4-yl)-2-methoxyiminoacetamido]-2-methoxy-3-cephem-4-carboxylate (syn isomer, 2.9 g.) in a mixture of tetrahydrofuran (110 ml.) and methanol (80 ml.) was treated in a similar manner to that of Example 8-(2) (diethyl ether was used for pulverization instead of diisopropyl ether) to give 7-[2-(2-formamido-5-bromothiazol-4-yl)-2-methoxyiminoacetamido]-2-methoxy-3-cephem-4-carboxylic acid (syn isomer, 1.2 g.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04703046
Source datasetuspto-grants-1987_10
ORD IDord-6ff1688fcf30457f9bc6245d1bc546b2
Source noteuspto-grants-1987_10