HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 20163828, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-(Bromomethyl)-4-(1,1-dimethylethyl)benzene | HCID 87836 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 20163828 | HCID 20163828 | — |
Reaction Steps
To a suspension of 23.0 g of anhydrous sodium carbonate in 75 ml of dry dimethylformamide is added 3.78 g of hydroxylamine hydrochloride followed by 24.72 g of p-tert-butylbenzyl bromide. After stirring at room temperature, the insoluble inorganic residue is removed by filtration and the mixture is concentrated under reduced pressure. Preparative liquid chromatography on the crude product affords a white solid, mp 108°-110° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04703073 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-1c808d3b2a6b460f9edb1b2f9afc495c |
| Source note | uspto-grants-1987_10 |