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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 256478Generated: October 30, 2026

2,6-Diethylaniline → 7-Ethylindole

https://huagongshe.com/reaction/256478

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DiethylanilineHCID 11369—
SolventWaterHCID 962—
Product7-EthylindoleHCID 272471141%

Reaction Conditions

Temperature610 °C

Reaction Steps

The reactor filed with Cu-chromite/BaO catalyst was heated to 610° C. Into the reactor was fed 68.4 g of 2.6-diethylaniline and 41.4 g of water per hour. The organic reaction product after 5 hours of such reaction conditions was collected and subjected to partial hydrogenation as described in Example 1. After filtering of the hydrogenation catalyst, 332.4 g of organic liquid containing 45.8 g percent of 2.6-diethylaniline and 41.0 percent of 7-ethyl indole was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04703126
Source datasetuspto-grants-1987_10
ORD IDord-5f61a3c7d5a542b78f62338db1c14ba5
Source noteuspto-grants-1987_10