HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Diaminopyridine → HCID 178494549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Diaminopyridine | HCID 8861 | — |
| Reactant | Methyl 4-methoxyacetoacetate | HCID 123500 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178494549 | HCID 178494549 | 20% |
Reaction Steps
A mixture of 21.8 g (0.2 mol) of 2,6-diaminopyridine and 29.2 g (0.2 mol) of methyl 4-methoxyacetoacetate in 400 ml of glacial acetic acid is stirred under reflux for 3 hours. After cooling, the precipitate is suction filtered and stirred with 150 ml of cold ethanol. 8 g (20%) of the title compound is obtained; m.p.: >290° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05258356 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-ec54c105bcdc42c9b929bb5aff0f1434 |
| Source note | uspto-grants-1993_11 |