Ethanolamine → HCID 19785401, compound

Participants

Reaction Conditions

Reaction Steps

1-Amino-2-methylthio-2-imidazoline tosylate (3.03 g) and isopropanol (7.5 ml) are placed in a 25 ml round bottom flask, then 2-aminoethanol (1.22 g) is added. The mixture is heated to about 40° C. to give a solution. After stirring overnight at 25° C., the mixture is concentrated to a thick colorless oil. Crystals were form upon storage at -20° C. Trituration with 10 ml isopropanol and filtration gives 2.68 g (84.8%) of 1-amino-2-(2-hydroxyethyl)-2-imidazoline tosylate as colorless crystals with mp 91.8°-92.7° C.

Provenance & Evidence