HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-Methoxy-3-oxo-2-phenylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | Phenylmalonic acid | HCID 75791 | — |
| Product | 3-Methoxy-3-oxo-2-phenylpropanoic acid | HCID 2817775 | — |
Reaction Steps
A mixture of phenylmalonic acid (3.6 g, 0.02 mol), boron trifluoride etherate (2.4 mL, 0.02 mol) and 0.8 mL of anhydrous methanol (0.02 mol) was refluxed and stirred for 24 hours. After cooling to room temperature, the reaction mixture was filtered and 20 mL of water was added.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05258388 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-351c1ca7330d49efafb2ef3ae97aebf1 |
| Source note | uspto-grants-1993_11 |