Benzylamine → HCID 19785254, Verbindung

Beteiligte Stoffe

Reaktionsschritte

A mixture of 26 parts of methyl 3-methyl-4-oxo-1-piperidinecarboxylate, 16.5 parts of benzenemethanamine, 2 parts of a solution of thiophene in ethanol 4% and 200 parts of methanol was hydrogenated at normal pressure and at room temperature with 3 parts of palladium-on-charcoal catalyst 10%. After the calculated amount of hydrogen was taken up, the catalyst was filtered off and the filtrate was evaporated to dry, yielding 40.2 parts of methyl 3-methyl-4-[(phenylmethyl)amino]-1-piperidinecarboxylate as a residue (interm. 26).

Herkunft & Nachweise