反应详情

This compound was prepared by coupling rac-3,4-dihydro-2-ethynyl-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol (1,15 g or 5 mmol) with 4-(trifluoroacetyl)-3,4-dihydro-6-iodo-2H-1,4-benzoxazine (1.95 g or 5.5 mmol) under the conditions described in Example 15. The product was isolated by chromatography over the 40 fold amount of silica gel methylene chloride. It was crystallized from ether/hexane and recrystallized twice from methanol to give colorless crystals with m.p. 153°-155°.

1. customThis compound was prepared
2. customThe product was isolated by chromatography over the 40 fold amount of silica gel methylene chloride
3. customIt was crystallized from ether/hexane
4. customrecrystallized twice from methanol
5. customto give colorless crystals with m.p. 153°-155°