Hydrochloric Acid → [(1S)-3-methyl-1-(3-oxo-propylcarbamoyl)-butyl]-carbamic acid benzyl ester

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By using an analogous procedure to that described for Reference Example 14, [(1S)-1-(3,3-diethoxy-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester (1.0 g, 2.5 mmol, obtained from Reference Example 15) in tetrahydrofuran was reacted with 0.5N hydrochloric acid (5 mL) for 15 min, to provide [(1S)-3-methyl-1-(3-oxo-propylcarbamoyl)-butyl]-carbamic acid benzyl ester (906 mg, 100%) as a white solid.

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