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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 257085Generated: October 25, 2026

N-Methylbenzylamine → 4-(N-benzyl-N-methylamino)-1-(4-nitrophenyl)piperidine fumarate

https://huagongshe.com/reaction/257085

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylbenzylamineHCID 7669—
ReactantFumaric AcidHCID 444972—
Reactant1-(4-Nitrophenyl)piperidin-4-oneHCID 3842562—
Product4-(N-benzyl-N-methylamino)-1-(4-nitrophenyl)piperidine fumarateHCID 19784395—

Reaction Steps

1-(4-Nitrophenyl)-4-piperidone was reacted in a similar manner to Example 2 with N-benzyl-N-methylamine and then with fumaric acid. 4-(N-benzyl-N-methylamino)-1-(4-nitrophenyl)piperidine fumarate was obtained. Melting point 183° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05260318
Source datasetuspto-grants-1993_11
ORD IDord-6f862ca5557847b495ce182f15eba9fb
Source noteuspto-grants-1993_11